Ossifying Fibromyxoid Tumor
Supplemental Studies
Immunohistology
| Four Largest Series | Including Other Reports | |
| S100 | 60-94% | 60-94% |
| Desmin | 10-50% | 10 to 50% |
| Smooth muscle actin | 0-5% | 2 to 50% |
| GFAP | 7% | 7-40% |
| CD57 | not tested | 60% |
| NSE | not tested | 60% |
| Keratin | 5-13% | 0-13% |
| EMA | 0-2% | 0-2% |
| Neurofilament | 90% | negative |
| MUC4 | 12% | not tested |
Malignant tumors are reported more frequently positive for keratin, EMA and smooth muscle actin and less frequently positive for S100 and desmin (Graham 2011)
INI1 staining shows a mosaic pattern with loss of expression in 30-60% of cells in 74% of cases (Graham 2011)
Genetic study
- No consistent clonal chromosomal abnormalities
