Mesenteric Fibromatosis

Clinical

Over age 5 years by definition
- Range 10-90 years, mean 40 years
10-15% of patients have familial adenomatous polyposis (FAP) / Gardner syndrome LINK to D1
- 9-15% of patients with FAP develop abdominal or intra-abdominal fibromatosis
Fibromatosis may develop following abdominal surgery
- Majority of FAP associated fibromatoses follow surgery
- 10% of sporadic mesenteric fibromatoses follow surgery
Not associated with pregnancy
Frequent recurrence
- 20-30% overall
- Recurrences may be locally aggressive and destructive

Deep fibromatoses differ primarily in their clinical association

	Abdominal	Extra-abdominal	Mesenteric	Pelvic / Retroperitoneal	Infantile
Pregnancy	+	-	-	-	-
Familial polyposis	rare	-	10-15%	-	-