Desmoplastic Fibroblastoma
Definition
- Densely collagenous lesion with low cellularity composed of spindled to stellate fibroblasts
Alternate / Historical Names
- Collagenous fibroma
Diagnostic Criteria
- May be subcutaneous or intramuscular
- Grossly well circumscribed
- Microscopically frequently infiltrates fat and muscle focally
- May be lobulated
- Size range 1-20 cm, median 3-4 cm
- Sparse spindled to stellate large fibroblasts
- Cytologically bland
- Fibromyxoid to densely fibrous background
- Hypovascular stroma
- Mitotic figures rare to absent
- No calcification or necrosis
Richard L Kempson MD
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Original posting: August 10, 2008
