Osteosclerotic Myeloma
Grading / Staging / Report
- Grading is not applicable
Durie-Salmon Staging System
- Stage I
- Hemoglobin >10 g/dL
- Serum IgG <5 g/dL
- Serum IgA <3 g/dL
- Normal serum calcium
- Urine monoclonal protein excretion <4 g/day
- No generalized lytic bone lesions
- Stage II
- Intermediate between stage I and III
- Stage III
- Hemoglobin <8.5 g/dL
- Serum IgG >7 g/dL
- Serum IgA >5 g/dL
- Serum calcium >12 g/dL
- Urine monoclonal protein excretion >12 g/day
- Advanced lytic bone lesions
The pathology report should contain the following information:
- Diagnosis in the World Health Organization (WHO) classification
- Equivalent diagnosis in other classifications used by relevant clinicians
- Results of supplementary studies if performed
- Relationship to other specimens from the same patient
- Information relevant to staging if available
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