Anus and Perianus: Condyloma Acuminatum
Supplemental Studies
Immunohistochemistry
- Staining for p16 is a useful surrogate for the presence of high risk HPV
- Most condylomas have low risk HPV
- Significance of demonstration of high risk HPV in an otherwise unremarkable condyloma is unclear
Genetic analysis
- Human papilloma virus (HPV) can be demonstrated by PCR
- Usually 6 and 11
