Anus and Perianus: Condyloma Acuminatum
Grading / Staging / Report
Grading
- The usual condyloma demonstrates low grade squamous intra-epithelial lesion (LSIL)
- Koilocytes are, by definition, at least LSIL
- High grade squamous intra-epithelial lesion (HSIL) may also be seen
| Low grade squamous intra-epithelial lesion (LSIL) | High grade squamous intra-epithelial lesion (HSIL) |
| Low nucleus/cytoplasmic (NC) ratio | NC ratio ≥ 1 |
| Orderly maturation | Disorderly maturation |
| Atypical cells confined to superficial layer | Atypical cells at all layers |
| Mitotic figures confined to basal layers unless inflamed | Mitotic figures at all levels |
| No atypical mitotic figures | Atypical mitotic figures may be seen |
Staging
- Not applicable
Report
- Should address in some way the question of level of dysplasia, for example:
- Condyloma acuminatum (LSIL), or
- Condyloma acuminatum, no evidence of high grade dysplasia
