Metaplastic Carcinoma of the Breast
Clinical
- Behavior is that of carcinoma rather than sarcoma
- First metastases are to lymph nodes
- Metastases are usually pure carcinoma
- Recent studies have questioned this, finding sarcoma-like behavior (recurrence without nodal metastases but with hematologic metastases) in lesions with minimal or only focal evidence of typical carcinoma and bland fibrous stroma (spindle cell carcinoma)
- 5 year survival reported as 47-68%