Ductal Carcinoma in Situ of the Breast
Variant: Mucinous Ductal Carcinoma In Situ
Diagnostic Criteria
- Extracellular mucin present within a duct involved by DCIS
- Epithelium must line all the spaces, separating mucin from stroma
- Distinguish from following:
- Invasive mucinous carcinoma has mucin in direct contact with stroma with cells floating in it
- DCIS with associated mucocele-like lesion has duct ruputure with an area of mucin spilled into stroma
- No cells should be floating in the mucin pools in the stroma
