Plasmablastic Lymphoma
Supplemental Studies
Immunohistology and Flow
- CD45RB minimal or negative
- B lineage markers
- CD20 minimal or negative
- CD79a frequent positive
- Immunoglobulin variable
- Plasma cell markers
- CD138 positive
- VS38 positive
- bcl6 variable, weak
- EBV LMP 5/16 variably positive
- HHV8 variably positive
- Ki67 >95% of cells positive
Genetic analysis
- EBV EBER FISH positive in 9/15 cases