Burkitt Lymphoma
Variant: Burkitt Lymphoma with Plasmacytoid Differentiation
- Abundant eccentric basophilic cytoplasm
- Stains for immunoglobulin
- Nuclei may be more pleomorphic than classical type
- Frequently with single prominent nucleolus
- Makes up about 20% of HIV associated non-Hodgkin lymphomas
- May also occur in children
- EBV positive by FISH in >50%
