Thymic Poorly Differentiated Neuroendocrine Carcinoma
Differential Diagnosis
| Metastatic Large or Small Cell Neuroendocrine Carcinoma of Lung | Primary Thymic Poorly Differentiated Neuroendocrine Carcinoma |
|---|---|
| History and imaging may reveal primary site | History and imaging should reveal no other primary site |
| TTF1 positive in >90% of lung neuroendocrine carcinomas | TTF1 negative (few tested) |
| Thymic Poorly Differentiated Neuroendocrine Carcinoma | Thymic Carcinoid / Well Differentiated Neuroendocrine Carcinoma |
|---|---|
| Nearly always cytologically malignant | Uniform cells with at most mild atypia |
