Thymic Carcinoma
Supplemental Studies
Immunohistology
Epithelial cell staining (thymocytes and T cells are CD5 positive)| CD5 | CD117 | CD57 | |
|---|---|---|---|
| Thymoma (except B3) | neg | 4% | pos |
| B3 Thymoma / Atypical Thymoma | 50% | <10% | pos |
| Thymic Carcinoma | 70-100% | >80% | rare |
- These markers should be used with caution in the distinction from lung and other carcinomas
- CD5 stains about 15% of lung squamous carcinomas
- CD117 stains about 20% of lung squamous carcinomas
- Basaloid carcinoma is p63 positive and negative for synaptophysin and TTF1
