Ectopic Hamartomatous Thymoma
Differential Diagnosis
Ectopic Hamartomatous Thymoma bears no resemblance to any type of thymoma
| Spindle Cell Lipoma | Ectopic Hamartomatous Thymoma |
|---|---|
| Lacks epitihelioid nests | Has epithelioid nests |
| Has ropy collagen | Lacks ropy collagen |
| Keratin, p63 and smooth muscle actin negative | Keratin, p63 and smooth muscle actin positive |
| Extragonadal Teratoma | Ectopic Hamartomatous Thymoma |
|---|---|
| In the neck, most are associated with the thyroid or ectopic thymus | Located in subcutaneous fat |
| May have a variety of differentiated tissues present | Restricted to spindled cells with squamous or glandular epithelium and fat |
| A variety of differentiated epithelial patterns may be present | Epithelium in nests or anastomosing cords |
| Spindle cell component may have a variety of phenotypes | Spindle cell component has a myoepithelial phenotype |
