Precursor T Lymphoblastic Leukemia / Lymphoma
Clinical
- Seen across both pediatric and adult age groups
- Most common in adolescent/young adult male
- Most common presentation is anterior mediastinal mass
- May present acutely with superior vena cava syndrome
- Other lymphoid sites (lymph nodes, Waldeyer’s ring) or soft tissue sites may also be involved
- Peripheral blood often shows high blast count
- High risk disease treated with aggressive chemotherapy and radiation
- Prognosis is best in the pediatric age group
