Surgical Pathology Criteria–

Neuroblastoma, Ganglioneuroblastoma and Ganglioneuroma

Differential Diagnosis

  Nblast ALL Ewing Sarc (PNET) Rhabdo MNTI DSCT Wilms Tumor
Synapto pos neg neg neg pos neg neg
NB84 pos neg neg neg neg neg neg
CD45RB (LCA) neg pos neg neg neg neg neg
CD99 neg pos pos neg rare neg neg
Myogenin neg neg neg pos rare neg neg
MyoD1 neg neg neg pos neg neg neg
Keratin neg neg rare rare pos pos neg
Desmin neg neg neg pos rare pos neg
WT1(C) neg neg neg neg neg pos pos
S100 neg neg rare neg rare neg neg
HMB45 neg neg neg neg pos neg neg
Nblast = Neuroblastoma; ALL = Precursor T Lymphoblastic Leukemia; Rhabdo = Rhabdomyosarcoma; MNTI = Melanotic Neuroectodermal Tumor of Infancy; DSCT = Desmoplastic Small (Round) Cell Tumor; Synapto = Synaptophysin

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