Surgical Pathology Criteria

Tenosynovial Giant Cell Tumor, Localized Type

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Differential Diagnosis

Diffuse Type Tenosynovial Giant Cell Tumor Localized Type Tenosynovial Giant Cell Tumor
Non-circumscribed Circumscribed
Usually associated joint involved Does not involve joint
Heavy iron pigmentation Variable pigmentation


Fibroma of Tendon Sheath Localized Type Tenosynovial Giant Cell Tumor
Paucicellular Cellular
Giant cells rare Giant cells in nearly all cases
Rare cellular fibromas of tendon sheath may be indistinguishable from giant cell poor tenosynovial giant cell tumors, but have the same behavior


Foreign Body Granuloma Localized Tenosynovial Giant Cell Tumor
Associated acute and chronic inflammation No associated inflammation



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