Superficial Angiomyxoma
Definition
- Bland, superficial myxoid lesion with prominent thin walled vessels
Alternate/Historical Names
- Cutaneous myxoma
Diagnostic Criteria
- Predominantly involves dermis and subcutis
- May involve skeletal muscle on face
- Multilobulated, poorly circumscribed
- Myxoid stroma
- Alcian blue positive, hyaluronidase sensitive
- May have acellular mucin pools
- Scattered bland stellate and spindled cells
- Occasional multinucleated cells
- Pleomorphism, mitotic figures rare
- Occasional intranuclear pseudoinclusions
- Many thin-walled small blood vessels
- Frequent neutrophils
- Entrapped epithelial component in 20-30% of cases
- Keratinous cyst
- Thin strands of squamous epithelium
- Basaloid buds
- If multiple or involving external ear, suggest Carney complex
Richard L Kempson MD
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Original posting/updates:: 5/2707, 2/5/10
