Ossifying Fibromyxoid Tumor
Differential Diagnosis
| Osteosarcoma | Ossifying Fibromyxoid Tumor |
|---|---|
| Cytologic atypia | Bland cytology |
| Tumor of bone | Most are superficial and small |
| Atypical "tumor" bone | Normal appearing lamellar bone |
| Glomus Tumor | Ossifying Fibromyxoid Tumor |
|---|---|
| No ossification | Frequent ossification |
| Actin positive, S100 negative | Actin variable, most are S100 positive |
| Myxoid Chondrosarcoma | Ossifying Fibromyxoid Tumor |
|---|---|
| No peripheral ossification | Frequent peripheral ossification |
| Most are deep and large | Most are superficial and small |
| PAS positive | PAS negative |

