Inclusions are keratin positive 100% (definitional)
EMA Frequently positive
Vimentin >95% positive
INI1 loss in 85%
Many studies report reactivity for some of the following, but a strict definition of extrarenal rhabdoid tumor does not permit such antigen expression:
Desmin, actin, myoglobin Negative
S100, HMB45 Negative
Neurofilament, GFAP Negative
CD34 Negative
Genetic analysis
Abnormalities of chromosome 22 have been demonstrated by various techniques:
Monosomy or deletion of the long arm of chromosome 22
