Surgical Pathology Criteria

Sclerosing Epithelioid Fibrosarcoma

Supplemental Studies

Immunohistology

MUC4 78% strong diffuse positive (Doyle 2012)
Vimentin positive
bcl2 90%
EMA 7/14 focal weak positive
S100 4/14 focal weak positive
Keratin 2/14 focal weak positive
NSE 2/14
Smooth muscle actin negative
Desmin negative
HMB45 negative
CD45RB (LCA) negative
CD68 negative
MUC4 also stains 100% of low grade fibromyxoid sarcoma

Genetic analysis

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