Surgical Pathology Criteria

Retroperitoneal and Pelvic Fibromatosis

Supplemental Studies

Immunohistology

Actin 50%
Desmin usually negative, occasionally focal
Beta-catenin 90%
CD117 CD117 frequently negative, variable reports of focal/weak staining
CD34 negative
S100 negative
Keratin negative
Estrogen receptor 0-10%
Progesterone receptor 0-25%
Response to hormone therapy is not related to receptor status
Reports of frequent strong reaction for CD117 appear to be due to a cross-reacting antibody (Miettinen 2001)

 

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