Surgical Pathology Criteria

Ischemic Fasciitis

Differential Diagnosis

 

 

Sarcoma, NOS Ischemic Fasciitis
Generally more cellular Generally less cellular
May show clear cytologic malignancy No clear cytological malignancy
May have atypical mitotic figures Atypical mitotic figures rare
Fat necrosis uncommon Fat necrosis characteristic

 

Myxoid Liposarcoma Ischemic Fasciitis
Little pleomorphism May be pleomorphic
Arborizing vascular pattern Granulation tissue but lacks arborizing pattern

 

Epithelioid Sarcoma Ischemic Fasciitis
Usually extremities of young patient Usually shoulder or hip of elderly patient
Usually brightly eosinophilic cytoplasm Cytoplasm usually basophilic or amphophilic
Keratin positive Keratin negative
Both are frequently CD34 positive

 

Myxofibrosarcoma Ischemic Fasciitis
Cytologically atypical to malignant No clear cytologic malignancy
Frequent atypical mitotic figures Atypical mitotic figures rare
Fat necrosis and fibrin rare Fat necrosis and fibrin characteristic
CD34 negative May be CD34 positive

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