Surgical Pathology Criteria

(Juvenile) Hyaline Fibromatosis

Differential Diagnosis

Myofibromatosis Hyaline Fibromatosis
Biphasic pattern with mature and immature areas No immature areas
Hemangiopericytic vascular pattern No hemangiopericytic pattern
Mature spindle cells with fusiform cytoplasm Scant cytoplasm
Actin positive Actin negative
Lack clinical features of syndrome Clinical features of syndrome

 

Neurofibroma Hyaline Fibromatosis
S100 positive S100 negative
Lack clinical features of syndrome Clinical features of syndrome

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