Surgical Pathology Criteria

Extra-abdominal Desmoid Fibromatosis

Supplemental Studies


Beta-catenin positive
Actin positive
Desmin usually negative, occasionally focal
CD34 negative
S100 negative
Keratin negative
Estrogen receptor 0-10%
Progesterone receptor 0-25%
Cathepsin-D positive
Response to hormone therapy is not related to receptor status


Trisomies 8 and 20, common in extra-abdominal desmoids are rare in abdominal desmoids

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