Surgical Pathology Criteria

Dermatofibrosarcoma Protuberans

Supplemental Studies

Immunohistology

CD34 Nearly 100%, extensive staining
Apolipoprotein D 90%
Factor XIIIa 75% but weak and focal
Actin Variable
Keratin Negative
S100 Negative
Desmin Negative

Genetic studies

t(17;22) with fusion of COL1A1 and PDGFB in all cases tested

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