Calcifying (Juvenile) Aponeurotic Fibroma
Differential Diagnosis
- Fibrous hamartoma of infancy
- Infantile desmoid fibromatosis
- Palmar or plantar fibromatosis
- Chondroma
- Calcifying fibrous pseudotumor
| Fibrous Hamartoma of Infancy | Calcifying Aponeurotic Fibroma |
|---|---|
| Nodules of immature mesenchyme | No immature mesenchyme |
| No palisaded pattern | Palisaded cells around nodules |
| No cartilage or calcification | Cartilage and calcification |
| Never on hands or feet | Frequent on hands and feet |
| Infantile Desmoid Fibromatosis | Calcifying Aponeurotic Fibroma |
|---|---|
| Not nodular | Nodular |
| No cartilage or calcification | Cartilage and calcification |
| Usually fat in center of lesion | Fat at periphery |
| Never on hands or feet | Frequent on hands and feet |
| Palmar or Plantar Fibromatosis | Calcifying Aponeurotic Fibroma |
|---|---|
| Rare under 20 | Predominantly <20 |
| Not calcified | Calcified |
| Rarely chondroid | Chondroid |
| No muscle or nerve infiltration | May infiltrate muscle and nerve |
| Chondroma | Calcifying Aponeurotic Fibroma |
|---|---|
| Predominantly adults | Predominantly <20 |
| No surrounding epithelioid cells | Epithelioid cells around nodules |
| No muscle or nerve infiltration | May infiltrate muscle and nerve |
| Calcifying Aponeurotic Fibroma | Calcifying Fibrous Pseudotumor |
|---|---|
| Cellular lesion | Paucicellular |
| Frequent chondroid stroma | No chondroid stroma |
| Restricted to hands and feet | Widely distributed |
| Broader areas of calcification | Focal small calcifications |
