Surgical Pathology Criteria

Lipofibromatosis

Supplemental Studies

Immunohistology

Spindled fibroblastic cells
CD99 10/12
CD34 12/13
Smooth muscle actin 10/12
bcl2 7/12
S100 5/14
Muscle specific actin 3/13
EMA 2/12
Desmin neg
Keratin neg
Beta-catenin neg

 

Pigmented spindle cells (rare)
Tyrosinase 2/2
MelanA 2/2
HMB45 1/2
S100 1/2

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