Does inflammatory myofibroblastic tumor qualify as dedifferentiation?
Lucas 2010 reported a series of 6 patients with components of atypical lipomatous tumor and inflammatory myofibroblastic tumor (IMT)
3 of 6 metastasized
However, of these three, two were not pure IMT in the dedifferentiated component, with the remainder being high grade sarcoma
The one pure case with metastasis is reported as to the inguinal region, where direct spread/recurrence through the inguinal canal appears to be a possibility
The histology of the metastases is not described
It is not clear from this report that IMT should be included in dedifferentiated liposarcoma