Squamoid Cyst of Pancreatic Ducts
Differential Diagnosis
- Lymphoepithelial cyst
- Dermoid cyst
- Epidermoid cyst in intrapancreatic accessory spleen
- Serous oligocystic adenoma
- Incidental squamous metaplasia
Most other cysts are easily distinguished by their non-squamous lining
| Lymphoepithelial Cyst of the Pancreas | Squamoid Cyst of Pancreatic Ducts |
|---|---|
| Surrounding dense lymphoid tissue | No surrounding lymphoid tissue |
| Overt keratinization | Non-keratinized |
| Usually peripancreatic | Intraductal |
| Squamoid Cyst of Pancreatic Ducts | Dermoid Cyst |
|---|---|
| No skin appendages or mesenchyme | Skin appendages and mesenchyme common |
| No overt keratinization | Keratinized |
| Epidermoid Cyst in Intrapancreatic Accessory Spleen | Squamoid Cyst of Pancreatic Ducts |
|---|---|
| Surrounded by splenic red pulp | Lacks surrounding splenic red pulp |
| May show overt keratinization | Non-keratinized |
| Involves tail of pancreas | Intraductal |
| Serous Macrocystic / Oligocystic Adenoma | Squamoid Cyst of Pancreatic Ducts |
|---|---|
| Lined by clear cells | Lined by squamoid cells |
| GLUT1 positive | GLUT1 at most focally positive |
Incidental squamous metaplasia of pancreatic ducts lacks cyst formation
