Surgical Pathology Criteria

Serous Microcystic Adenoma of the Pancreas

Supplemental Studies

Histochemistry

Lining cells
PAS+, diastase sensitive pos
Mucin neg

Immunohistology

Lining cells

CK7 pos
CD8 pos
CK18 pos
CK19 pos
MUC6 pos
Neuron specific enolase pos
Alpha inhibin 75%
34BE12 / CK5 50%
Chromogranin neg
Synaptophysin neg
Estrogen receptor neg
Progesterone receptor neg
Alpha 1 antitrypsin neg
CK20 neg
Smooth muscle actin neg
CEA neg
No stromal staining with any of the above markers

 

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