Surgical Pathology Criteria

Serous Cystadenocarcinoma of the Pancreas

Differential Diagnosis

Serous Microcystic Adenoma Serous Cystadenocarcinoma of the Pancreas
Circumscribed intrapancreatic mass Requires vascular invasion, adjacent organ invasion or metastases
  • Serous adenoma and cystadenocarcinoma are histologically indistinguishable
  • Rare cases have been reported of resected non-invasive serous cystadenomas that recurred later with metastases
  • Serous Macrocystic / Oligocystic Adenoma Serous Cystadenocarcinoma of the Pancreas
    Mass limited to pancreas, without vascular invasion Requires vascular invasion, adjacent organ invasion or metastases

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