- Pancreatic or peripancreatic cystic lesion formed by resorption of fat necrosis
- Located in or adjacent to the pancreas
- Lacks epithelial lining
- Wall may range from granulation tissue to fibrosis
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
Original posting: February 28, 2008
Last update: April 25, 2009
No diagnostically useful stains
- Lack of epithelial lining effectively separates it from other cystic lesions
- Requires adequate sampling
- Adjacent stroma may be hypercellular, resembling the ovarian type stroma of mucinous cystic neoplasms
- As above, lack of epithelial lining separates the two
- Secondary to pancreatitis
- No association with neoplasm
- May erode into ducts or vessels
Cystic Pancreatic Lesions
- Adsay NV. Cystic lesions of the pancreas. Mod Pathol. 2007 Feb;20(Supp1):S71-S93).
- Solcia E, Capella C, Kloppel G . Tumors of the Pancreas, Atlas of Tumor Pathology, AFIP Third Series, Fascicle 20, 1997.
- Basturk O, Coban I, Adsay NV. Pancreatic cysts: pathologic classification, differential diagnosis, and clinical implications. Arch Pathol Lab Med. 2009 Mar;133(3):423-38.