Mucinous Cystic Neoplasm of the Pancreas
Differential Diagnosis
| Intraductal Papillary Mucinous Neoplasm |
Mucinous Cystic Neoplasm of the Pancreas |
| Usually over age 50 |
Usually under age 50 |
| Male>female |
Nearly all female |
| Involves segments of ducts |
Does not communicate with ducts |
| Multiple adjacent cystic spaces |
If multilocular, usually many smaller cysts within a circumscribed larger cyst |
| Extensive papillae formation |
Minimal papillae |
| No ovarian type stroma |
Ovarian type stroma |
| May be associated with colloid carcinoma |
No association with colloid carcinoma |
| Mucinous Cystic Neoplasm of the Pancreas |
Intraductal Oncocytic Papillary Neoplasm |
| Lacks oncocytic epithelium |
Oncocytic epithelium |
| Lacks intracytoplasmic lumens and cribriform pattern |
Prominent cribriform pattern formed by intracytoplasmic lumens |
| Complex papillae not seen |
Complex arborizing papillae |
| Cellular ovarian type stroma |
Paucicellular stroma |
| No communication with ducts |
Communicates with duct system |
| Intraductal Tubular Adenoma |
Mucinous Cystic Neoplasm of the Pancreas |
| Nodular intraductal growth |
Mucin filled cyst or cysts |
| Low grade atypia |
Atypia may vary from low to high |
| Males and females affected |
Nearly all female |
| Involves segments of ducts |
Does not communicate with ducts |
| Extensive tubule formation |
No tubules |
| No ovarian type stroma |
Ovarian type stroma |
