Lymphoepithelial Cyst of the Pancreas
Differential Diagnosis
- Dermoid cyst
- Epidermoid cyst in intrapancreatic accessory spleen
- Squamoid cyst of pancreatic ducts
- Pancreatic pseudocyst
Most other cysts are easily distinguished by their non-squamous lining
| Lymphoepithelial Cyst of the Pancreas | Dermoid Cyst |
|---|---|
| No skin appendages or mesenchyme | Skin appendages and mesenchyme common |
| Sebaceous differentiation focal at most | Sebaceous differentiation may be prominent |
| Lymphoepithelial Cyst of the Pancreas | Epidermoid Cyst in Intrapancreatic Accessory Spleen |
|---|---|
| Surrounding dense lymphoid tissue | Surrounding splenic red pulp |
| Lymphoepithelial Cyst of the Pancreas | Squamoid Cyst of Pancreatic Ducts |
|---|---|
| Surrounding dense lymphoid tissue | No surrounding lymphoid tissue |
| Overt keratinization | Non-keratinized |
| Usually peripancreatic | Intraductal |
| Lymphoepithelial Cyst of the Pancreas | Pancreatic Pseudocyst |
|---|---|
| Squamous lining (may be partially denuded) | No epithelial lining |
| Uniform dense lymphoid stroma | Variable surrounding inflammation |

