Surgical Pathology Criteria

Lymphoepithelial Cyst of the Pancreas

Differential Diagnosis

Most other cysts are easily distinguished by their non-squamous lining

Lymphoepithelial Cyst of the Pancreas Dermoid Cyst
No skin appendages or mesenchyme Skin appendages and mesenchyme common
Sebaceous differentiation focal at most Sebaceous differentiation may be prominent

Lymphoepithelial Cyst of the Pancreas Epidermoid Cyst in Intrapancreatic Accessory Spleen
Surrounding dense lymphoid tissue Surrounding splenic red pulp

Lymphoepithelial Cyst of the Pancreas Squamoid Cyst of Pancreatic Ducts
Surrounding dense lymphoid tissue No surrounding lymphoid tissue
Overt keratinization Non-keratinized
Usually peripancreatic Intraductal

Lymphoepithelial Cyst of the Pancreas Pancreatic Pseudocyst
Squamous lining (may be partially denuded) No epithelial lining
Uniform dense lymphoid stroma Variable surrounding inflammation

Stanford Medicine Resources:

Footer Links: