Intraductal Papillary Mucinous Neoplasm of the Pancreas
Differential Diagnosis
| Intraductal Papillary Mucinous Neoplasm | Mucinous Cystic Neoplasm of the Pancreas |
|---|---|
| Usually over age 50 | Usually under age 50 |
| Male>female | Nearly all female |
| Involves segments of ducts | Does not communicate with ducts |
| Multiple adjacent cystic spaces | If multilocular, usually many smaller cysts within a circumscribed larger cyst |
| Extensive papillae formation | Minimal papillae |
| No ovarian type stroma | Ovarian type stroma |
| May be associated with colloid carcinoma | No association with colloid carcinoma |
| Intraductal Papillary Mucinous Neoplasm | PanIN |
|---|---|
| Usually clinically detectable | Usually not clinically detectable |
| Grossly visible | Not grossly visible |
| May have well formed papillae | No well formed papillae |
| May be associated with colloid carcinoma | No association with colloid carcinoma |
| MUC2 or CDX2 may be positive | MUC2 and CDX2 negative |
