Acinar Cell Cystadenoma of the Pancreas
Differential Diagnosis
- Distinction from serous and mucinous cystic lesions is made by identification of the nature of the lining cells
- Acinar cell cystadenocarcinoma
| Acinar Cell Cystadenoma | Mucinous Cystic Lesions | Serous Cystic Lesions |
|---|---|---|
| Lined at least in some areas by cells with granular eosinophilic apical cytoplasm | Mucin positive but lacks granular cytoplasm | Clear cytoplasm, PASd negative |
| Acinar Cell Cystadenoma of the Pancreas | Acinar Cell Cystadenocarcinoma of the Pancreas |
|---|---|
| Cytologically bland | Cytologically moderately atypical with prominent nucleoli |
| Mitotic figures absent to very rare | Mitotic figures frequent |
| No infiltration | Frequently infiltrative |
