Acinar Cell Carcinoma of the Pancreas
Clinical
- Rare
- 1-2% of pancreatic neoplasms
- Most age 40-70
- Rare cases do occur in children
- 10% exhibit lipase hypersecretion syndrome
- Subcutaneous fat necrosis and polyarthralgia
- No clinical difference between pure and mixed acinar-neuroendocrine carcinomas
- Poor prognosis but slightly better than ductal carcinoma
- 36-72% 5 year survival (La Rosa 2012)
