Nodular Lymphoid Hyperplasia
Definition
- Pulmonary mass or masses formed by reactive lymphiod tissue
Alternate/Historical Names
- Pseudolymphoma
Diagnostic Criteria
- Clinical
- Most are incidental findings
- Age 19-90
- Most reported not associated with autoimmune disease or immunodeficiencey
- Benign
- High resolution computed tomography (HRCT)
- Discrete nodule or nodules
- Usually 2-4 cm
- Most are subpleural but do not form pleural plaques
- Discrete nodule or nodules
- Histopathologic features
- Well defined mass or masses
- Intervening lung is normal
- Lacks capsule and structure of an intrapulmonary lymph node
- Prominent germinal centers
- Interfollicular sheets of plasma cells
- Mixed polytypic plasma cells, B and T cells
- Interfollicular fibrosis may be present
- Well defined mass or masses
Robert V Rouse MD
Department of Pathology
Stanford University School of Medicine
Stanford CA 94305-5342
