Surgical Pathology Criteria

Xp11 / TFE3 Translocation Carcinoma of the Kidney

Supplemental Studies

Immunohistology

Keratin weak to neg
EMA, CK7 neg
AMACR/racemase/P504S pos
CD10 pos
CD117 neg
TFE3 or TFEB

pos

MelanA, HMB45 neg-90% pos, frequently weak

Molecular Genetic Study

 

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