Surgical Pathology Criteria–

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Supplemental Studies

Immunohistology

Phenotype of sarcomatoid component

Broad spectrum anti-keratin	95-100%
EMA	50-100%
High MW keratin	0-20%*
Vimentin	33-100%
Actin	33%
Desmin	neg

*Few studies, but HMW keratin only reported in collecting duct carcinomas

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