Surgical Pathology Criteria

Sarcomatoid Renal Cell Carcinoma

Supplemental Studies

Immunohistology

Phenotype of sarcomatoid component
Broad spectrum anti-keratin 95-100%
EMA 50-100%
High MW keratin 0-20%*
Vimentin 33-100%
Actin 33%
Desmin neg
*Few studies, but HMW keratin only reported in collecting duct carcinomas

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