Oncocytic Papillary Renal Cell Carcinoma
Supplemental Studies
Immunohistology
- The only consistent immunohistologic finding appears to be racemase positivity
- The remainder of the results are highly variable from report to report including
- CK7, cKIT (CD117), EMA, CD10, RCC membrane antigen, vimentin
Genetic studies
- About half of reported series find abnormalities consistent with papillary renal cell carcinoma
- Trisomy 7 and 17
- Loss of Y chromosome
- Some reports, however, do not find these abnormalities