Multilocular Cystic Renal Cell Carcinoma
Differential Diagnosis
| Conventional Clear Cell Renal Cell Carcinoma | Multilocular Cystic Renal Cell Carcinoma |
|---|---|
| Both cystic and solid areas | No solid areas |
| Nodules of clear cells are expansile and/or invasive | Nests of clear cells are not expansile or invasive |
| May be low or high grade | Must be low grade (1 or 2) |
| Multilocular Cystic Renal Cell Carcinoma | Cystic Nephroma |
|---|---|
| 3:1 M:F | Nearly all female |
| Nests of clear cells in stroma | No nests of clear cells in stroma |
| Lacks cellular ovarian type stroma | Ovarian type stroma |
| Tubulocystic Carcinoma of the Kidney | Multilocular Cystic Renal Cell Carcinoma |
|---|---|
| Lining cells have abundant eosinophilic cytoplasm | Clear cells line cysts |
| No nests of clear cells | Nests of clear cells in stroma |
| High grade nuclear features | Low grade nuclear features |
