Surgical Pathology Criteria

MiT Family Translocation Renal Cell Carcinoma

Supplemental Studies

Immunohistology

Keratin weak to neg
EMA, CK7 neg
AMACR/racemase/P504S pos
CD10 pos
PAX8 pos
CA9 typically neg
Cathepsin K variable
CD117 neg
TFE3 or TFEB

pos

MelanA, HMB45 Variable, frequently weak

Molecular Genetic Study

 

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