Pseudomyxoma Peritonei
Differential Diagnosis
| Pseudomyxoma Peritonei |
Peritoneal Carcinomatosis |
| Primary is mucinous neoplasm of high risk of recurrence of appendix (rarely from teratomas) |
Primary is mucinous carcinoma of any GI site |
| Paucicellular implants |
Implants usually cellular |
| Non-invasive implants |
Invasive implants |
| Low grade cytology |
May have high grade cytology |
| Simple or focally proliferative epithelium |
Complex cribriform epithelium |
| No signet ring cells |
May have signet ring component |
| No nodal or parenchymal metastases (except ovary) |
Frequent nodal and parenchymal metastases |
| Many recurrences, eventual fatalily |
Generally rapidly fatal |
The distinction is critical
