Family history of polyps and colorectal carcinoma only
May have family history of characteristic associated neoplasms
Duodenal adenoma in 18%
Duodenal adenoma rare
Germline mutation detected in MUTYH gene
No MUTYH mutation
No evidence of mismatch repair deficiency
Genetic and immunohistologic evidence of mismatch repair deficiency
Autosomal recessive
Autosomal dominant
MUTYH associated polyposis may be very difficult to distinguish clinically from HNPCC as it has fewer adenomas and later presentation and frequent right sided carcinoma
