Juvenile Polyposis of the Gastrointestinal Tract
Supplemental Studies
Immunohistology
- No useful stains
Genetic Studies
- Mutations in:
- MADH4 5-15%
- Includes most cases with gastric involvement
- BMPR1A 25%
- PTEN 5%
- These patients probably really have Cowden Syndrome
- May be useful within a kindred to determine who gets screened
- MADH4 5-15%
