Surgical Pathology Criteria

Gastroblastoma

Differential Diagnosis

Gastroblastoma Carcinosarcoma
Young adults Generally older patients
Cytologically bland Malignant epithelial and stromal elements

Gastroblastoma Gastric Synovial Sarcoma
Components may be indistinct Components generally distinct
FISH negative for SS18 abnormalities FISH shows evidence of SS18 rearrangement

Gastroblastoma Gastric Teratoma
Young adults Generally infants
Only two components Multiple tissue types

Gastroblastoma Mesothelioma
Negative for CK5/6 and calretinin CK5/6 and calretinin positive
Not serosal based Based in serosa

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