Squamous Carcinoma of the Colon and Rectum

Differential Diagnosis

	Colorectal Squamous Carcinoma	Colorectal Adenosquamous Carcinoma	Colorectal Adenocarcinoma with Squamous Metaplasia
Squamous component	Malignant	Malignant	Benign
Glandular component	Absent	Malignant	Malignant

Both components must be more than focal

Squamous Carcinoma of the Anus	Colorectal Squamous Carcinoma
Must involve anal canal	Must not involve the anal squamous mucosa

Some require that colorectal SCC be at least 5-7 cm from the anus