Surgical Pathology Criteria

Hyperplastic Polyp of the Colon and Rectum

Supplemental Studies

Immunohistology

  Ki67 CK20
Normal mucosa Limited to basal ¼ Limited to surface
Hyperplastic polyp Expanded to basal 1/3-1/2 Expanded to luminal 1/2-2/3
SSA Patches of staining at all levels Patches of staining at all levels
TSA Mainly localized to ectopic crypts Irregular staining of luminal surface
Usual adenoma High overall Random
(based on Torlakovic 2008)

Genetic Analysis

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