Appendiceal Mucinous Neoplasm with Low Risk of Recurrence

Differential Diagnosis

Appendiceal Mucinous Neoplasms

Mucinous Adenoma/Cystadenoma	Mucinous Low Risk of Recurrence	Mucinous High Risk of Recurrence	Mucinous Adenocarcinoma
No extra-appendiceal mucin	No epithelium in extra-appendix mucin	Epithelium present in extra-appendiceal mucin	Epithelium may be present in extra-appendiceal mucin
Non-invasive epithelium may be present in intramural mucin	Non-invasive epithelium may be present in intramural mucin	Non-invasive epithelium may be present in intra and extramural mucin	Invasion by jagged neoplastic glands
Margin of resection must be clear	Margin may be involved	Margin may be involved	Margin may be involved
Benign, no recurrences	Very few recur, 0% mortality	Frequently recur, 50% 5 year, 20% 10 year survival	<10% 10 yr survival